Sunday 24 June 2012

The Lab is on YouTube

Our laboratory has received support from the University of Lethbridge at many levels.  We, in return, are pleased to participate in University initiatives to reach out and let you know who we are and what we do.  The U of L has produced a number of videos to celebrate its 45th anniversary.  Amongst these, you will find the Cancer Cell Laboratory on YouTube.  Although I do most of the talking, one gets a glimpse of the laboratory and the people who do the experiments.  See us at:

Cancer Cell Laboratory on YouTube

We appreciate the University of Lethbridge's support for research.

Wednesday 13 June 2012

And the big paper is in press

Our manuscript is accepted in the Biochemical Journal.  It is a too brief moment of satisfaction of completing a project.  A special thanks to the experimentalists who succeeded in converting the complex problem of cell division with damaged DNA into a powerful experimental model. Of the cell lines we tested, HT-29 cells have features that provide a window of the key transition point of entry into mitosis after a checkpoint. 
What's next - we have developed a non-radioisotope assay to measure enzyme activity in mitotic cells; we are testing how to block checkpoint adaptation, and we are looking very closely at the DNA in cancer cells that survive checkpoint adaptation. 
If interested, please feel free to contact us for questions, reagents or a copy of the paper.